14 year old girl with fever and swelling of left upper limb and right lower limb k/c/o SCA

  25/7/2023.

14 year female child who is k/c/o sickle cell anemia came with c/o fever and swelling of left upper limb and right lower limb associated with pain since 3 days 

Fever which is of high grade not associated with chills and rigors , cold ,cough, sore throat, chest pain , palpitations,sweating,abdominal pain,vomitings,diarrhoea,decreased urine output .

No h/o hematuria , melena,bleeding gums,petechia,menorrhagia .

HISTORY OF PRESENTING ILLNESS:

Patient was apparently asymptomatic 11 years ago (1/4/2012) when she was 3 years old she was admitted in the hospital with c/o fever , cough, vomitings she was diagnosed to have sickle cell anemia (Hb electrophoresis was done) and was given blood transfusion and treated with Inj ampicillin and folic acid 

2. On 23/9/14 

She was taken to the hospital with complaints of fever, cough ,cold since 1 week and diagnosed with bronchopneumonia ( chest x ray showed left lower lobe consolidation). She was treated with Inj Augmentin and whole blood transfusion was given .

3.on 16/11/15 

She was admitted with c/o  fever, cough ,cold since 3 days 

Ceftriaxone , meropenam and vancomycin was given 

Whole blood transfusion was done 

4.on 14/11/13

Admitted for fever ,cough, cold since 4 days 

Diagnosed with lower respiratory tract infection.

Treatment: cefotaxime (7 days ),azithromycin ( 3 days ) 

Blood transfusion done 

5. Admitted on 4/4/14 

C/o cough, cold, high grade fever since 4 days 

Diagnosed as SCA with right upper lobe consolidation 

Treatment: Inj piptaz (10 days ) , Inj amikacin (7 days ) 

Inj vancomycin given for 2 days but stopped because of allergic reaction.

6. Admitted on 16/9/14 

C/o high grade Fever with chills since 2 days 

Diagnosed as SCA with bronchopneumonia 

Treatment: 1 mg Augmentin for 5 days 

Blood transfusion was done . 

7. Admitted on 24/12/14 

C/o cold,cough, fever since 2 days breathless since 1 day 

Diagnosed as SCA with bronchopneumonia.

Treatment: inj amoxyclav for 7 days .

8. Admitted on 8/7/15 

C/o Fever , rapid breathing,cough since 2 days 

Diagnosis:SCA with bronchopneumonia 

Treatment: inj amikacin for 5 days , Inj Augmentin for 10 days . 

9. 6/11/15 

C/o cough , cold since 3 days fever since 1 day presented with sob 

Diagnosis: SCA with bronchopneumonia.

Treatment: inj ceftriaxone ( 1 day ) meropenam and Inj vancomycin for 10 days 

Whole blood transfusion. 

Pneumococcal 23 strain vaccine given on 6/11/15 

On 20/1/16 

C/o Fever, generalised myalgia and arthralgia , pain abdomen 

Treatment: inj meropenam for 7 days 

                 Inj vancomycin for 7  days 

Admitted on 17/12/19 

C/o pain abdomen ( on and off since one month in epigastric pain and left hypochondrium )

Vomitings since afternoon.

Diagnosis: SCA with vasooclusive crisis with acute pancreatitis 

Treatment:PIPTAZ for 5 days 

                 Tab hydroxyurea 

Admitted on 17/2/2020 Follow up 

Admitted on 21/3/2020 

SCA  with acute pancreatitis follow up 

Admitted on 1/2/2022 

C/o abdominal pain since 2 days associated with vomitings and epigastric pain ( gradually progressive) 

Serum amylase : 944 IU /lit 

Treatment: tab cefixime , tab levofloxacin for 5 days 

Admitted in GM on 15/7/2022

C/o knee pain since 3 days 

Diagnosis: SICKLE CELL ANEMIA with VASOOCLUSIVE  CRISIS 

Treatment:PRBC transfusion , penicillin g given 

Admitted on 20/8/2022

C/o knee pain since 3 days 

SCA WITH VASOCLUSIVE CRISIS.

Admitted on 15/3/2022 

,C/o pain in b/L knees and loin pain 

Treatment: tab penicillin po/od 

                  hydroxyurea .

On 25/7/23 

She came with c/o fever and swelling of left upper limb and right lower limb associated with pain since 3 days . 



FAMILY HISTORY: 

Patients father mentioned that they had first baby boy who died at at the age of 3 due to similar complaints.

She has 2 younger siblings sister and brother 

Both are healthy, younger sister was tested for sickle cell anemia and was negative. 

No other members in the family have  similar complaints. 



       




Sickle cell trait of her parents.

GENERAL EXAMINATION:

Patient is CONCIOUS , COHERENT,COOPERATIVE 

Pallor - present 

Icterus , cyanosis, clubbing , lymphadenopathy absent 

Vitals :

Temperature :98.5 F

Pulse rate : 82 bpm 

Bp: 110/60 mmhg 

RR:18 cpm 

SYSTEMIC EXAMINATION: 

CVS : s1,s2 heard no murmurs 

RS : BLAE present,NVBS 

CNS : NFND 

P/A : soft , non tender .

Diagnosis: 

K/c/o sickle cell anemia since 11 years with vasocclusive crisis ( left upper limb and right lower limb) pyrexia under evaluation. 

           

                







         Investigations: 25/7/23


 





27/7/23





27/7/23




Treatment given : 

IV fluids 2 NS @ 75 ml / hour 

Inj neomol IV/sos 

Inj TRAMADOL IV / TID 

TAB HYDROXYUREA 500 mg po/bd 

TAB SHELCAL PO/bd 

TAB OROFER PO/OD 

TAB CHYMEROL FORTE PO/TID 

TAB PCM 650 mg po/TID 


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